ea0037ep706 | Pituitary: basic and neuroendocrinology | ECE2015
Schnyder Ingeborg
, Strausz Konrad
, Koch Gilbert
, Walti Carla
, Pfister Marc
, Allolio Bruno
, Fenske Wiebke Kristin
, Christ-Crain Mirjam
Background: Copeptin is the C-terminal portion of the precursor of vasopressin. In contrast to vasopressin copeptin is stable in vitro and easy to measure. Similar kinetics of both peptides have been described in different trials. However, the physiological area of normality of copeptin has never been evaluated.Methods: We measured plasma copeptin, sodium, and osmolality levels in 93 healthy volunteers at baseline, during/after i.v. infusion of ...